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However, the negative effects of medicines can force some patients to avoid this treatment. Jonathan Cole published an article in the American Journal of Psychiatry entitled: Emergence of Intense Suicidal Preoccupation During Fluoxetine Treatment. Another severe unwanted effect is persistent pulmonary hypertension in the Newborn (PPHN), that's equivalent to high blood pressure in babies' lungs. It's just such a monstrous task it's overwhelmed me on several occassions. also appear to reduce the effectiveness of neurotransmitters thereby developing a resistance to neurotransmitters. Was I really speaking with Jesus or was the Effexor making me hallucinate. If I leave the house and forget to bring along some water, I get a lttle bit panicky until I can purchase a bottle, because even 5 minutes without something to wet my whistle can feel like an eternity. Many individuals may feel more severe unwanted effects when taking Effexor XR. References:Some People with Depression Actually Do Worse With Medication, Study Finds - Types of Antidepressants - Cymbalta Side Effects. Regular drug screening and medication levels may be important. Well, thanks to my inquisitive mind, I asked her, when she prescribed Effexor, what are the minimum dosage was. For example - let's say in a level of 10 you have panic-like symptoms, at a level of 20 you've anxiety, at 30 perhaps depression, at 40 migraines as an example, and normal function between 50-75. It seems how the "non-responders" -- those that show no improvement by 50 % months -- can get sicker due to side-effects from your medication. Antidepressants going with the therapy of the drug are observed closely by themselves members for that unusual behaviour. Effexor was the very first drug I was prescribed to handle my multiple sclerosis-induced anxiety and occasional severe depressive symptoms. I might notice a difference within the straight tripping if I eat. 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