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Using two separate drugs to shed pounds can be very effective there are combinations as you're watching FDA now awaiting approval. When dealing with fat loss and the those who go through it you ought to err on the side of caution and allow the FDA do its job and demand some research be done so the public recognizes the side effects and risks of the medications before we take them. Keep in mind that drug companies are in business to generate money and that they would say almost anything to keep people on his or her medications. Researchers found that participants investing in this drug for the year, lost weight within four weeks and have kept the weight off through the 56 weeks of the study. Contrave is a combination of the drugs naltrexone and bupropion, which appears to reflect a brand new trend of weight-loss drugs that are made up of multiple active ingredient, which can make them more efficient and safer. Combo-pilling may be the newest fad or also the newest in the future under scrutiny and for that reason it is just more publicly known in recent months, comb-pilling for weight loss has been around since the eighties. The biggest reason that employing a combination of pills is becoming popular is the fact that as of right now there are no long term prescription diet pills that have been licensed by the FDA other than orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications although some people might of the combinations happen to be rejected or have yet to be licensed by the FDA. Seizures certainly are a side effect with Contrave and shouldn't be taken in individuals with seizure disorders. The drug could also raise hypertension and heart rate, and really should not be used in people who have a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with the drug. The FDA also warned that Contrave can raise hypertension and heartrate and must not be used in patients with uncontrolled high hypertension, along with by a person with heart-related and cerebrovascular (blood vessel dysfunction impacting the brain) disease. Patients using a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes with a boxed warning to alert medical professionals and patients towards the increased probability of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stopping smoking. 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