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Recent research has found out that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent possess a particular mutation that creates them prone to benefit from naltrexone, in contrast to about 20% of Caucasians and fewer than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director in the UCLA Addictions Laboratory. The findings are available online ( in the journal Neuropsychopharmacology and will be published in an upcoming print edition of the journal. Using two separate drugs to shed weight can be very effective you can find combinations as you're watching FDA now awaiting approval. When dealing with fat loss and the people that go through it you need to err assisting caution and allow the FDA do its job and demand some study be done so the public knows the side effects and perils associated with the medications before we take them. Keep in mind that drug companies come in business to earn money and that they would say everything to keep people on the medications. Researchers found out that participants using this drug for the year, lost excess weight within a month and have kept the body weight off through the 56 weeks with the study. Contrave can be a combination in the drugs naltrexone and bupropion, which usually reflect a new trend of weight-loss drugs which can be made up of more than one active ingredient, that might make them more potent and safer. Combo-pilling is the newest fad or even better the newest in the future under scrutiny and for that reason it is just more publicly known although in the past, comb-pilling for weight reduction has been around since the eighties. The biggest reason that utilizing a combination of pills is becoming popular could be the fact that since right now there aren't any long term prescription weight loss supplements that have been approved by the FDA besides orlistat. The truly disturbing part is doctors are prescribing these combinations of medications even though some of the combinations are actually rejected or have yet to be authorized by the FDA. Seizures really are a side effect with Contrave and really should not be taken in people who have seizure disorders. The drug can also raise blood pressure level and heart rate, and shouldn't be used in individuals with a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy using the drug. The FDA also warned that Contrave can raise blood pressure and heartbeat and must not used in patients with uncontrolled high blood pressure levels, as well as by you aren't heart-related and cerebrovascular (circulation dysfunction impacting the mind) disease. Patients having a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes having a boxed warning to alert health care professionals and patients for the increased risk of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for smoking cessation. Most of the combinations which can be used to enhance weight loss involve an amphetamine as well as an antidepressant. Phentermine and Prozac certainly are a popular combination that were around for a while, and even though it has been around no one wants to truly combine both and try to get FDA approval to market it as a weight loss pill. Right there should raise some red flags if the greedy pharmaceutical companies should not be involved in combining medications and selling them something has to be wrong with all the combination. In fairness there is one weight-loss combination pill that is in front of the FDA now Contrave?which couples naltrexone, utilized to treat alcohol and substance abuse, with the antidepressant bupropion (Wellbutrin, Zyban) many experts have given the try to move forward by an FDA advisory committee, but since yet hasn't been approved.