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Using two separate drugs to shed weight can be very effective you will find combinations before the FDA now awaiting approval. When dealing with weight reduction and the people who go through it you need to err assisting caution and allow FDA do its job and demand some investigation be done in order that the public knows the side effects and risks of the medications before we bring them. Keep in mind that drug companies come in business to generate income and that they would say everything to keep people on their own medications. Researchers found that participants using this drug for the year, dropped a few pounds within one month and have kept the body weight off throughout the 56 weeks from the study. Contrave is often a combination with the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs which are made up of many active ingredient, which might make them more effective and safer. Combo-pilling may be the newest fad or in addition to this the newest ahead under scrutiny and for that reason it is just more publicly known lately, comb-pilling for weight reduction has been around since the eighties. The biggest reason that using a combination of pills is starting to become popular could be the fact that as of right now there aren't any long term prescription slimming capsules that have been licensed by the FDA aside from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications although some people might of the combinations are actually rejected or have yet to be authorized by the FDA. Seizures certainly are a side effect with Contrave and mustn't be taken in people with seizure disorders. The drug could also raise hypertension and heartrate, and must not be used in people with a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise hypertension and pulse rate and must 't be used in patients with uncontrolled high blood pressure level, along with by anyone with heart-related and cerebrovascular (circulation system dysfunction impacting the mind) disease. Patients with a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes having a boxed warning to alert health care professionals and patients for the increased probability of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for smoking cessation. Approving a drug using this many potentially lethal unwanted side effects is inconsistent using the mission statement in the FDA. The power of the drug manufacturing lobby is blatantly evident inside approval of several drugs requiring 'post-marketing' studies which can be clearly significant to overall drug safety within the US.