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The U.S. Food and Drug Administration reviewed Contrave on December 7, and approved the drug 13-7, stating the main benefit of the drug outweighs potential risk of a possible boost in blood pressure. Using two separate drugs to shed pounds can be very effective you will find combinations as you're watching FDA now awaiting approval. When dealing with fat loss and the people who go through it you should err on the side of caution and allow the FDA do its job and demand some research be done so that the public understands the side effects and perils associated with the medications before we drive them. Keep in mind that drug companies have been in business to generate money and that they would say almost anything to keep people on their own medications. Researchers found out that participants investing in this drug for the year, lost weight within four weeks and have kept the extra weight off through the 56 weeks from the study. Contrave is often a combination with the drugs naltrexone and bupropion, which appears to reflect a fresh trend of weight-loss drugs which can be made up of more than one active ingredient, which can make them more effective and safer. Combo-pilling will be the newest fad or also the newest into the future under scrutiny and therefore it is just more publicly known in recent months, comb-pilling to lose weight has been around since the eighties. The biggest reason that utilizing a combination of pills is becoming popular could be the fact that at the time of right now there aren't any long term prescription weight loss supplements that have been approved by the FDA besides orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications even though some of the combinations have been rejected or have yet to be approved by the FDA. Seizures can be a side effect with Contrave and mustn't be taken in people with seizure disorders. The drug may also raise blood pressure levels and heartrate, and really should not be used in individuals with a history of heart attack or stroke in the previous six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise blood pressure levels and pulse rate and must stop used in patients with uncontrolled high blood pressure level, and also by a person with heart-related and cerebrovascular (circulation dysfunction impacting the mind) disease. Patients having a history of heart attack or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes using a boxed warning to alert physicians and patients towards the increased chance of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stop smoking. From a psychiatric perspective, evidence shows that the ordinary neural mechanism for goal-directed behavior continues to be hijacked by the addiction, and malfunctions in a way that its ordinary functions are exaggerated and fixated on its object. An object generates a stimulus along with the person engages in a "goal-directed behavioral response" that creates a "natural high"(Bostwick & Bucci, 2008).