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Using two separate drugs to shed pounds can be very effective you'll find combinations while watching FDA now awaiting approval. When dealing with weight loss and the those who go through it you should err assisting caution and let the FDA do its job and demand some research be done in order that the public is aware of the side effects and perils associated with the medications before we bring them. Keep in mind that drug companies are in business to make money and that they would say anything to keep people on their own medications. Researchers found that participants using this drug to get a year, lost weight within 4 weeks and have kept the body weight off throughout the 56 weeks of the study. Contrave is often a combination from the drugs naltrexone and bupropion, which appears to reflect a fresh trend of weight-loss drugs which are made up of many active ingredient, which might make them far better and safer. Combo-pilling will be the newest fad or better yet the newest ahead under scrutiny and so it is just more publicly known recently, comb-pilling for losing weight has been around since the eighties. The biggest reason that utilizing a combination of pills is starting to become popular is the fact that at the time of right now there aren't any long term prescription slimming capsules that have been approved by the FDA apart from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications although some people might of the combinations are already rejected or have yet to be authorized by the FDA. Seizures are a side effect with Contrave and shouldn't be taken in individuals with seizure disorders. The drug can also raise hypertension and heartbeat, and shouldn't be used in people with a history of cardiac event or stroke in the earlier six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy using the drug. The FDA also warned that Contrave can raise hypertension and heartrate and must not used in patients with uncontrolled high hypertension, as well as by you are not heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients with a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes having a boxed warning to alert medical professionals and patients on the increased chance of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for smoking cessation. "There were no warning signs of depression or suicidal thoughts in trial participants," said Fujioka.