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Combo-pilling will be the newest fad or in addition to this the newest in the future under scrutiny and so it is just more publicly known lately, comb-pilling for losing weight has been around since the eighties. The biggest reason that by using a combination of pills is becoming popular may be the fact that by right now there are not any long term prescription weightloss pills that have been authorized by the FDA besides orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications however some of the combinations happen to be rejected or have yet to be licensed by the FDA. Seizures certainly are a side effect with Contrave and really should not be taken in individuals with seizure disorders. The drug may also raise blood pressure and pulse rate, and really should not be used in those with a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy using the drug. The FDA also warned that Contrave can raise hypertension and heart rate and must 't be used in patients with uncontrolled high blood pressure, along with by you aren't heart-related and cerebrovascular (circulation dysfunction impacting the mind) disease. Patients having a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes having a boxed warning to alert medical researchers and patients to the increased chance of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for quitting smoking. 
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