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Using two separate drugs to shed pounds can be very effective you'll find combinations as you're watching FDA now awaiting approval. When dealing with weight-loss and the those who go through it you should err on the side of caution and let the FDA do its job and demand some study be done in order that the public recognizes the side effects and hazards of the medications before we drive them. Keep in mind that drug companies will be in business to generate money and that they would say everything to keep people on their medications. Researchers found out that participants investing in this drug for the year, lost excess weight within four weeks and have kept the body weight off during the entire 56 weeks with the study. Contrave is a combination from the drugs naltrexone and bupropion, which appears to reflect a new trend of weight-loss drugs which might be made up of several active ingredient, which might make them more efficient and safer. Combo-pilling will be the newest fad or even better the newest to come under scrutiny and therefore it is just more publicly known recently, comb-pilling for weight loss has been around since the eighties. The biggest reason that by using a combination of pills is becoming popular is the fact that since right now there aren't any long term prescription weight loss supplements that have been authorized by the FDA apart from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications even though some of the combinations are actually rejected or have yet to be approved by the FDA. Seizures really are a side effect with Contrave and shouldn't be taken in those with seizure disorders. The drug can also raise blood pressure levels and heartbeat, and must not be used in people with a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with the drug. The FDA also warned that Contrave can raise hypertension and heartbeat and must 't be used in patients with uncontrolled high blood pressure levels, and also by anyone with heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients which has a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes having a boxed warning to alert medical professionals and patients on the increased probability of suicidal thoughts and behaviors connected with antidepressant drugs. 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